AI-powered precision neuropsychiatry
Our iMAGiNE™ predictive biomarker platform delivers personalized assessments of brain health to accelerate safer and more effective therapeutics for complex patients.
We fuse generative AI with computational neuroscience
Sama Therapeutics is advancing "software as medical device" for a range of indications, including cognitive, affective, interoceptive, and substance use disorders. The company's agile SaaS platform, iMAGiNE™, analyzes the transdiagnostic efficacy of pharmaceutical and neurostimulation modalities through precision clinical trials, deep phenotyping, causal inference, digital twins & preclinical translation. We invite you to join our mission unlocking brain health through integrative neurotechnology.
Our solutions
Accelerate clinical trials and therapy development
Using cross-validated AI/ML models, our biomarker platform de-risks both clinical and preclinical R&D to bring innovative therapies to patients sooner. We generate prospective insights on dosing, efficacy, adverse events, placebo, indication selection, digital twins & much more.
Help providers deliver effective treatments
Our clinic integrations eliminate the trial-and-error approach to mental health and neurological care. Through the analysis of LLMs, psychometrics, EEG/ECG, and VR assessment, we help care providers better understand patient conditions, measure progress & improve outcomes.
Empower everyone to own & track their brain health
There’s nothing more critical to overall performance than optimizing the brain’s function. Our technology generates reports and insights for biohackers, early adopters of psychedelic medicine, longevity & anti-aging, or anyone that values objective measurements into their health.
Our partners
Award-winning predictive capabilities
Our approach ranks #1 among dozens of data science teams in an international competition to validate clinically-actionable biomarkers.
We can differentiate major psychiatric disorders (MDD, ADHD, PTSD, OCD, SCZ) by predicting treatment response > 50% better than current state of the art, regardless of the treatment modality: “transprognostic.”
Meet the executive & computational team
We bring together the sharpest minds in computational neuroscience, generative artificial intelligence, integrative neurotechnology, psychedelic medicine & clinical care innovation, including experimental psychiatrists and open science pioneers with 100's of high impact papers & patents.
Consulting & operations
An extraordinarily interdisciplinary group of academic, nonprofit, and industry experts across pharmaceutical, medical device, neuroimaging, multiomics, natural language processing, legal & regulatory domains.
Our advisory board
We’re fortunate to draw on the collective wisdom of academics and repeat founders who have successfully commercialized AI platforms.
Our publications
